Prevalence of Peripheral Neuropathy in Libyan Patients with Type 2 Diabetes Mellitus Using SemmesWeinstein Monofilament Examination

الملخص

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM). However, there is very limited data
available about the risk factors of DPN in the Libyan population.
Objective: To investigate the prevalence of DPN in Libyan patients with type 2 diabetes (T2D) and to find out its relation with
patient demographics and associated risk factors including glycosylated hemoglobin (HbA1c), body mass index (BMI), duration
of the disease, comorbidities, biochemical data, vitamin D, and vitamin B12 levels.
A cross-sectional study recruited 117 patients with type 2DM. Demographics (age, sex, and duration of DM), and BMI were
all recorded. Laboratory results of fasting blood glucose (FBG), postprandial blood glucose (PPBG), Hemoglobin A1c, cholesterol, high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL-C), triglycerides, vitamin B12 and
Vitamin D levels were all analyzed. DPN was assessed using the 10-g Semmes-Weinstein monofilament examination (SWME).
Among 117 type 2 diabetes patients, we found that 16/117 (13.68%) tested positive for the 10 g monofilament examination
(DPN+ve). The mean age range was 57.53± 11.48 years, with a median diabetes duration of 10 years. BMI was 31.825.58± kg/
m2
, and HbA1c was 8.55 ±1.99%. The study found that age, diabetes duration, FBG, and PPBG were the most significant risk
factors for DPN. Binary logistic regression analysis revealed that only age, duration of diabetes, FBG, and PPBG were the only
significant risk factors for DPN in our population and they predicted 73.8% of the model correctly.
Conclusion: The 10g monofilament test was effective in detecting early symptoms of DPN in 13.68% of patients with type 2
diabetes mellitus with older age, longer duration of diabetes, higher FBG and PPBG, and higher HbA1c as independent predictors of risk for DPN.