استجابة صور الرنين المغناطيسي للجادولنيوم في أورام الدماغ

Abstract

Gadolinium (Gd-DTPA) is well known contrast agent which has been used to enhance images in Magnetic Resonance Imaging (MRI). Gadolinium is characterized by magnetic properties of being able to influence the relaxation time of proton in tissue. This would cause an increase in intensity of the signal in T1- weighted image (i.e. during longitudinal relaxation time) and decrease it in T2- weighted image (transverse relaxation time). The aim of this work is to study signal intensity between lesion and normal tissue in brain by using statistically calculated parameters. The Grey Level Co-occurrence Matrix (GLCM) is a statistical method which will be implemented on MRI images. MRI system with 1.5 Teslaat Tripoli Medical Center is used to image patients before and after injection of the contrast agent. The results show an increase in pixel intensity after contrast agent is introduced in area with infected tissue. Digital verification could be used to distinguish between infected and normal tissue.