Evaluation and Comparison Study of Various Antidandruff Shampoos in Tripoli Libya

الملخص

Shampoo is a hair care product used for the removal of oils, dirt, skin particles, dandruff, environmental pollutants and other
contaminant particles that gradually build up in hair. Dandruff is a common disorder affecting the scalp, causing a major
problem in many peoples nowadays, it is a clinical condition caused by Malassezia species which is of great cosmetic concern
all over the world. Dandruff cannot be completely eliminated but can only be controlled by fungistatic ingredients in anti
dandruff shampoos. Many antidandruff shampoos in Tripoli markets available from various sources, imported from different
countries, whether medicated or non-medicated marketed to combat the problem of dandruff. The aim of the present study was
to evaluate different medicated and non-medicated anti-dandruff activity of shampoo on the bases of scientifically measurable
properties to judge their safety and efficacy. Twelve shampoos were randomly collected and purchased from different markets in
Tripoli and were compared and evaluated according to their physicochemical properties including organoleptic characterization
by visual inspection, determination of pH, assurance of solid content, viscosity, surface tension measurement, foam stability,
dirt dispersion, cleansing efficiency, wetting time determination. Additionally, antimicrobial activity, skin irritation tests, and
evaluation of label information on the package were conducted. Stability testing was also performed under different temperature
and humidity conditions.
The evaluated shampoos were visually attractive in color, with pleasant fragrances, smooth consistency with no aggregation, and
good froth ability, detergency, good cleansing, and low surface tension. The pH range was from 6.14 to 8.88, The percentage
of solid contents ranges from 15.5% to 38.5%, viscosity was in range of 0.9238-1.7199 CST, surface tension was found to be
27-33 mN/m, and foam volume range from 110 - 190 ml. cleaning action range from 35.5% - 68%, wetting time range from 13
to16.9 second. The antimicrobial activity to investigate antibacterial and antifungal activities was done using cup plate method
against Staphylococcus aureus, Malassezia furfur, Candida albican and the zone of inhibition was observed all the selected
shampoos were proved affective against antibacterial but remarkable result against fungi and has shown 12-26 mm inhibitory
action, the highest zone of inhibition was obtained by shampoo number 6 against Candida albican. Stability and acceptability
of formulations during the storage for three months in 4 and 45 °C did not markedly affect the characteristic of shampoo so
indicated physical and chemical stability.
All these are the ideal characters for good quality of shampoo to be used in daily life. The study indicates that medicated anti
dandruff shampoos were proved to be more effective compered to non-medicated shampoos